CBD Oil bioavailability makes them the top deliverable method! CBD will not disappoint you!

20 mins read
reviewedMedically Reviewed
Dr. Gary Mendelow
Medical doctor Reviewed: February, 2022

CBD oil tinctures are the primary method of delivering CBD since they have a high bioavailability index and allow the cannabinoid to hit the system fast for the onset of effects. Yet, finding the best CBD oil tinctures is not easy with the many CBD brands in the hemp space. This article helps you know THE BEST CBD OIL TINCTURES OF 2022, shares the criterion for spotting the best ones and answers people’s common questions about CBD tinctures.


Trying CBD oil. Most easy way to have it with you.

There are many ways to take CBD, and CBD oil tinctures top the list. Not only do they allow you to feel the CBD benefits, but they boast high bioavailability indices. This way, CBD reaches your system fast and allows the effects to surface in no time. 

CBD oil tinctures may be bitter and earthy, but they are the fastest when discussing CBD results. As if this is not enough, there is no temptation to snack with CBD oil tinctures, so the possibility of taking too much than the body can accommodate is low. The alcohol base in the oil tinctures also ensures that the cannabinoids last longer than other deliverable methods. 

Treat this article like a primer; it sheds light on the best CBD oil tinctures of 2022 and discusses the criterion for choosing such from the CBD space with many companies and each claiming to be the best. The blog also explains how CBD oil tinctures work and answers the common questions people have about the oil tinctures. First, let’s appreciate the parent compound.



CBD Oil bioavailability makes them the top deliverable method! CBD will not disappoint you in delivering it and making it last long.


CBD has become a compound of major interest and is part of the cuisine and the beauty industry. The supplement world has also embraced it, and you can find many CBD products being sold as supplements or supplements featuring CBD as part of the ingredient list. Thus, the increasing popularity of CBD makes it necessary to expand more on it. 

Massi et al. (2006) and Bauer et al. (2020) defined CBD as a non-psychoactive chemical compound in hemp plants. Hemp is an example of a cannabis plant which boasts multiple compounds called cannabinoids. There are more than 100 cannabinoids in nature, with CBD and THC being of much scientific concern. Although THC and CBD can be extracted from hemp, they vary significantly. Schlienz et al. (2018) commented that THC is psychoactive. However, CBD is non-psychoactive, and taking it will not make you high.


CBD seems to have many benefits since Watt & Karl (2017) reported that it is therapeutic. A Forbes Health (2022) report showed that more than 60% of US adults take some form of CBD and believe it is therapeutic. Yet, the body cannot absorb CBD as it is. 

Manufacturers present CBD in delivery methods, which are forms the body can absorb. CBD oil tinctures are the primary delivery method for CBD. They are liquid-based CBD forms taken orally, sublingually, or added to foods and drinks.


The liquid-based forms of CBD delivery methods are CBD oils and tinctures. They are delivered orally and sublingually but can also be added to foods and drinks. Nonetheless, they differ subtly. CBD oils feature oils as the base carrier. 

They may have MCT coconut, hempseed, or extra virgin oils. Meanwhile, CBD oil tinctures feature alcohol as the base. In most cases, the alcohol used as the base carrier is the same in extracting CBD. Both an extraction agent and the base carrier, alcohol in the tinctures makes them have a prolonged shelf life.


Before you sign up for the CBD regime and make CBD oil tinctures part of your regime, you need to understand how the oil tinctures work. CBD studies are limited, and much is yet to be understood about cannabinoids, including how CBD oil tinctures work. 

The current line of understanding has everything to do with a network of endocannabinoids, endocannabinoid receptors, and enzymes in the body making up the endocannabinoid system (ECS).

CBD Oil bioavailability makes them the top deliverable method! CBD will not disappoint you in delivering it and making it last long.

Julia Davis

According to Zou & Kumar (2018), critical processes in the body like digestion, reproduction, mood changes, and pain management depend on the ECS. As long as the enzymes keep fueling the system to produce more endocannabinoids that bind to the receptors, the body keeps the processes in equilibrium. 

Meanwhile, the slightest interruption affects the endocannabinoid, leading to negative feedback in the processes relying on the system. This is where cannabinoids like THC and CBD come in. Mechoulam & Parker (2013) reported that THC binds to CB1 and CB2 receptors, but how CBD interacts with the ECS is unclear. Still, Watt & Karl (2017) found CBD therapeutic, suggesting that its interaction with the ECS is positive.


CBD oil tinctures are the primary way of letting CBD get to your system, and you may wonder why. For the most part, their bioavailability makes them the top deliverable methods. When you take CBD oil tinctures sublingually or orally, it reaches the system quite fast. In fact, sublingual administration is even more effective since the blood vessels under the tongue allow the CBD to reach the bloodstream even faster and steers positive effects. 

If you want CBD to express the desired effect fast, you could go for CBD oil tinctures. We cannot also ignore the fact that the alcohol base in the tinctures adds to the longevity of the product, whose shelf life expands and can last longer than a normal oil. CBD oil tinctures may be bitter, but they effectively deliver CBD and do not disappoint you in delivering it and making it last long.


Do CBD oil tinctures have cons or are they flawless delivery methods? Of course, they have flaws. For the most part, the alcohol base in the alcohol means they are bitter, and administering the cannabinoid through this method may not be the best-tasting option one would go for. Besides, no single delivery method is 100% bioavailable. 

CBD oil tinctures are highly bioavailable and let CBD into the system fast, but this does not mean that all the CBD in them gets to the system. Still, we appreciate that unlike CBD edibles like gummies, honey sticks, and desserts, the oil tinctures do not come with the temptation to snack based on their taste. Many CBD companies offer oil tinctures in flavored options to allow people to mask the bitter taste a little.



Trying CBD oil. Most easy way to have it with you.


Do CBD oil tinctures have any health benefits? The Forbes Health (2022) report mentioned earlier reported that more than 60% of the US adults have used CBD in one form or the other and believe in the CBD therapy. In fact, the report showed that they believe in CBD helping with pain, anxiety, sleep, and many other issues. How true are these claims? So far, we know that the FDA has not approved CBD usage to treat any medical condition. Still, studies see potential in CBD oil tinctures and believe that only more research is needed to prove that CBD can offer more. For instance; 




CBD Oil bioavailability makes them the top deliverable method! CBD will not disappoint you in delivering it and making it last long.

  • Pain Management 

Vučković et al. (2018) reviewed CBD studies from 1975 to March 2018. The review examined the effect of CBD oil tinctures on pain and reported that the cannabinoid could fight pains, including fibromyalgia, cancer, and neuropathy. Shannon et al. (2019) also mentioned pain as one thing CBD could help with.

  • Improved Sleep Quality 

Many CBD fans who take CBD oil tinctures believe that the cannabinoid might be all they need to manage sleep. People have sleep issues, and the Center for Disease Control & Prevention (2022) reported that more than a third of US adults do not get enough sleep. Can CBD oil tinctures treat sleep issues? Murillo- Rodriguez et al. (2014) stated that CBD could improve one’s sleep since it regulates the circadian rhythm and the sleep-wake cycle. Studies are yet to determine if CBD indeed helps with sleep or the compounds added to it do.

  • Anxiety management 

The current economic conditions result in anxiety, and so does the Covid- 9 pandemic, which has left people jobless or deceased. Of course, people have always been anxious, but the situation gets worse as time advances. Can CBD oil tinctures treat anxiety? According to García-Gutiérrez et al. (2020), CBD fights anxiety, stress, and such anxiolytic issues. 

  • Stress and Depression Management 

Without good management of anxiety, it could lead to stress, escalating into depression. Every other day, more people suffer anxiety and depression. The antidepressants that people use are either too expensive or do not work for some people. Can CBD oil tinctures treat depression? There is not enough scientific evidence to prove this. However, according to Silote et al. (2019), CBD seems to be a better antidepressant. Yet, the FDA has not approved using the cannabinoid to manage depression, and even as people use it for this purpose, it is good to know this.


With many CBD companies in the hemp space and each claiming to offer the best CBD oil tinctures, it is almost hard to find the best products. The lack of regulation in the CBD industry is yet another challenge. It is not unusual to come across companies that claim to offer the best products when this is not the case. Our criterion is simple and looks at the factors below in determining the best CBD oil tinctures. Perhaps focusing on these factors could be all you need to spot good CBD oil tincture;

  1. Source of CBD; although CBD comes from hemp and other cannabis plants as well, we ensure that our CBD oil tinctures use hemp as the primary hemp source online with the 2018 Farm Bill.
  2. The origin of hemp; the US Hemp Authority ensures hemp farmers stick to the latest regulations in producing hemp, hence why we opt for US-sourced hemp in making CBD.
  3. 3rd party tests; reputable brands conduct 3rd party tests to reveal the purity of their products and their cannabinoid profile.
  4. CoA; we recommend buying CBD oil tinctures from companies that offer a CoA as proof of 3rd party tests, and word of mouth is not enough.
  5. Environmental factors; we focus on companies that use organic hemp to manufacture CBD oil tinctures.
  6. Ingredient list; the oils in this article feature all-natural ingredients. Remember, the fewer the ingredients, the better.
  7. Contaminant purity; we look at the CoA of the recommended brands to ensure they are pure and have no standard contaminants in the form of solvents, toxins, animal derivatives, and more.
  8. Company reputation and customer feedback; we review the website for the companies’ reputation and the feedback section to know how clients find the CBD oil tinctures before recommending them as the best.


Are you set to buy the best CBD oil tinctures? We are ready to take you through the process. This section features the best brands for CBD oil tinctures which we have chosen based on the criterion above;



The JustCBD store was established in 2017, and the many years in the hemp space have given CBD users confidence in its products. It boasts a large CBD inventory, with CBD oil tinctures being among the many products. 

They feature many potencies, from as low as 50 mg to as high as 1500 mg, providing something for novice and veteran users. Besides, the JustCBD oil tinctures come in many flavors, are 3d party tested, and the results are posted online in the CoA section. Every order comes with free shipping.



The term Naturals in Nuleaf CBD company means that the company uses all-natural ingredients in producing CBD oil tinctures. Besides, their CBD oil tinctures are free of pesticides, as shown by the 3rd party test results posted on the brand’s website. 

The company conducts 3rd party tests, and the CoA reveals that it is one of a kind. At a 300 mg- 6000 mg CBD concentration range, the brand offers CBD oil tinctures for novice and veteran users.

Although CBD oil tinctures deliver CBD to the system fast, they are bitter and earthy, and many find it hard to take them. FAB CBD oil tinctures have no aftertaste and are great for you if you find it difficult to administer CBD oils by other brands. 

They come in multi-flavored options, and you can enjoy them in berry, vanilla, and peppermint, among many other flavors. They are non-GMO and made from all-natural products. Through the 30-day money-back guarantee, FAB CBD allows clients to return orders and ask for refunds or exchanges.



Lazarus is one of the great CBD players in the hemp space and boasts a large inventory with almost every CBD delivery method. Its CBD oil tinctures come in many potencies and feature some of the highest concentrations at 6000 mg CBD. 

Besides, they come in flavored options, with Blood Orange, Mocha, Yuzu, and Vanilla options. The company offers after 60% discount to veterans and people with substandard lifestyles. It also conducts 3rd party tests for all products and has CoA on the website. 



CBDistiller is a member of the US Hemp Authority and ensures that it uses high-quality hemp in manufacturing its CBD oil tinctures. The hemp plants are grown in Colorado, one of the US’s richest hemp-growing zones. Besides, the brand uses the cleanest extraction method to strip CBD from the hemp surfaces, ensuring that the final products have no contaminant traces. 

The company also allows all CBD users to enjoy the full entourage effect of multiple compounds in CBD oil tinctures since they have CBG as part of the active compounds in the tinctures.  



Although Cheef Botanicals is new in the hemp space following its inception in 2019, it is one of the major players in the CBD arena. It conducts 3rd party tests on all the CBD oil tinctures and other products and posts the results online. Besides, the founders have more than 25 years of combined experience in the food industry, which is why you can trust the products. 

The CBD oil tinctures feature a large potency range of 300 mg- 3000 mg, and whether you are a CBD veteran or novice, there is a CBD oil tincture for you. The tinctures are vegan, so many users relate to them. The brand offers free shipping on all orders, and through the 30-day money-back guarantee, you can return an order based on dissatisfaction and request for exchange or refund.



Royal CBD does not bear the term royal for no reason. It offers high-quality CBD oil tinctures, which are tested by 3rd party and the results posted online. Although it was launched in 2018, it has grown and now features many products in its inventory. When it saw its inception, it had CBD gummies as its flag-bearing products. 

Now, it offers quality CBD oil tinctures, spa collections, pet items, and many other CBD products. The brand offers free shipping on all orders, and through the 30-day money-back guarantee, you can return orders and request an exchange or refund.



Hemp Bombs should be your favorite CBD company if you like CBD in flavored options. The CBD oil tinctures come in orange, acai berry, and watermelon flavors, among many others. 

With a 300 mg- 4000 mg CBD concentration range, the brand has novice and veteran CBD users covered. 

The oil tinctures are tested by 3rd parties, and every order comes with free shipping. Besides, they feature isolate-based CBD formulations and are great if you need THC-free CBD oil tinctures.



The person behind it is Joy Smith, who believed in CBD therapy and the cannabinoid’s role in helping with sleep. 

The brand’s products are 100% organic, made from pure Colorado hemp, and 3rd party tested, with results being posted on the brand’s website. There are 450, 900, 1350, and 2250 mg CBD concentrated options, meaning that novice and veteran CBD users can have something for themselves. 

The company features summer flavors in the CBD oil tinctures, which you can enjoy in mint, orange blossom, and summer lemon, among many other options. 



CBD Essence started off as a small CBD brand and was incepted by Suzie Salah and Don Ballou, a couple that believed in CBD therapy. 

They were more than fit to start the brand with many years of combined experience in the hemp and wellness field. 

There are many options you can sign up for to enjoy the tinctures. For instance, you can take the vanilla, apple green, peppermint, and grape flavors. Besides, they also boast a large CBD concentration range of 300- 4000 mg, which is why veterans and novices relate to the brand’s products.



Do you want a highly bioavailable CBD oil tincture for mental focus on clarity? Visit Spruce; the brand’s CBD oil tinctures are specifically formulated for your mind. 

They come in full-spectrum formulation, allowing you to enjoy them with other cannabinoids as well. The brand uses the clean CO2 extraction method to strip CBD off hemp spaces. 

This ensures the tinctures are pure, as shown by the 3rd party test results posted on the brand’s website.



Green Roads came to light in 2012 but has been in the market for longer. Besides the many years of experience that makes it stand out, it has licensed professionals in its team, all the more why you can trust its products. 

Its THC-free CBD oil tinctures come in many potency options, but the company recommends the 1500 mg concentrated CBD oil for mental focus. The 3rd party tests are one reason you can trust the brand, and you can access their results by checking the CoA online.


CBD oil tinctures are the primary method for delivering CBD to the body. They are bioavailable, and when taken sublingually, the CBD in them gets to the bloodstream fast. 

The interaction between CBD and the endocannabinoid system results in the positive effects linked to the cannabinoid. Many people in CBD therapy and take it for pain, sleep issues, stress, and depression. 

Still, there is not enough scientific evidence to prove this, although the existing studies see great potential in the cannabinoid. 

This article is about what CBD oil is, how it works, and what its benefits are. It also addresses people’s common questions about CBD oil tinctures, including whether they make you high and if they show up in drug tests. Lastly, you can also peer into this article to have insight into the best CBD oil tincture brands.

Frequently Asked Questions about CBD Tinctures 

People have many questions about CBD oil tinctures, and you likely do. Whether you are new to the cannabinoid or have been using CBD oil tinctures for some time, there must be that one thing you die to know about CBD oil tinctures. For instance. 

Many newcomers to CBD oil tinctures may want to know if taking the cannabinoid will make them high. To understand this, one needs to know how drug tests work. A drug test looks for THC and its metabolites. 

Since CBD is not THC, it will unlikely show up in drug tests. Yet, it is worth noting that there is more to this, and the type of CBD formulation matters. When the tincture oil in question had THC as one of the active compounds, you may test positive for drug tests.

CBD is an umbrella term for the non-psychoactive cannabinoid, and if you are going to buy CBD oil tinctures, you need to know the various types there are. You can enjoy any CBD product in one of the following formulations, which translate to the types;

  1. Full-spectrum CBD oil; features CBD and the whole range of cannabinoids in hemp plants. Besides, they feature additional compounds like terpenes and flavonoids, which, according to VanDolah et al. (2019), add up to a full entourage effect.
  2. Isolate-based CBD; is the exact opposite of full-spectrum CBD and features pure cannabinoid. It does not have additional cannabinoids, terpenes, and flavonoids. 
  3. Broad-spectrum: is in between full-spectrum CBD and isolates. It has all the cannabinoids, terpenes, and flavonoids in full-spectrum CBD but not THC.

The compounds making up the CBD oil tinctures you are taking are important and determine whether you will fail a drug test or pass it.

Since there are three types of CBD oil tinctures (and other deliverable methods for the cannabinoid), you certainly want to know the best of the best. The three CBD oil tinctures are not any better than the other. In fact, the varieties ensure CBD users with varying needs have something that matches their needs. 

For instance, if you are new to CBD and want to enjoy it in the purest form, isolate-based CBD oil tinctures. Meanwhile, if you want a full entourage effect, you can go for full-spectrum CBD. Better yet, if you want a non-THC full entourage effect, broad-spectrum CBD oil tinctures might be all you need. At the end of the day, no CBD formulation is inferior and what you choose depends on your unique needs.

Do you want to take CBD oil tinctures? You need to understand how long you might have to wait for the effects to show up. There is no one-time-fits-all sort of a thing for CBD oil tinctures. Rather, the cannabinoid takes different times to work in different users. Much about how long the effects take to surface depends on the factors below;

  1. Metabolism; if your cells produce CBD faster, you can look forward to experiencing the effects fast. And the reverse is also true.
  2. CBD exposure; when you are new to CBD, the effects may take long to come, which might change considerably with time.
  3. The potency of the CBD oil tinctures; although this is not always the case for every CBD user, the potency of the tincture matters, and the more potent they are, the faster you expect the effects to show up.
  4. How much CBD oil tincture you take; although you need not overdose on the cannabinoid, a higher concentration of the tincture might translate to fast effects. 
  5. Body composition; your unique body factors like genes might influence your genetic makeup, ultimately determining how long the effects take to surface.

After the CBD effects show up, how long do they last? This is yet another question whose answer you need to know before trying any CBD oil tinctures. 

There is no exact time CBD oil tinctures take to work, and the same is true for how long the effects last. If they come fast, you expect them not to last long. 

If you waited in them for long, they might last longer. Your CBD metabolism also matters. The faster the metabolic rates, the faster the effects will take to go away.

Many CBD brands are offering CBD oil tinctures as part of their inventory. With many such compounds, choosing good CBD oil tinctures is not easy. 

However, focusing on environmental factors, contaminant purity, the presence of a CoA, and the ingredient list will help your search more rewarding when you land a quality product. For the most part, look for CBD companies dealing in organic CBD products made from 100% pure organic US-based hemp. 

Ensure that they offer CoA as proof of 3rd party tests and that the CoA shows contaminant purity.

When you are going to buy CBD oil tinctures, you need to be sure of many things, including how much CBD should be in your tinctures. Of course, this depends on many factors, and it does not come as a surprise that one CBD fan might go for strong CBD oil tinctures while others go for less potent ones. 

If you are new to CBD, you need to keep the CBD amounts in your CBD oil tincture as low as possible until you get used to the cannabinoid. Meanwhile, as you get used to the cannabinoid, you may feel ready to focus on CBD oil tinctures with high CBD amounts. 

The severity of the condition and why you are into a CBD regime also determine the amount of CBD in the CBD oil tinctures. People taking CBD oil tinctures for general well-being might be at home with little CBD in the products, while severe health conditions might call for stronger CBD oil tinctures. 

How much CBD oil tincture should one take? The CBD concentration in the oil tinctures is one thing and how much of the cannabinoid you can take is another. 

When trying CBD oil tinctures for the first time, you may need to take it slow and limit the amounts to maybe half a dropper. Meanwhile, veteran CBD users understand their system well and can take more CBD oil tinctures. Your CBD metabolism also matters. 

For instance, high metabolism allows you to take high amounts of CBD oil tinctures, but if your rates are slow, your system might not be able to take more CBD oil tinctures.

Before joining the CBD regimen for any product, you need to understand the concept of potency. Potency is the quotient of total CBD concentration and the volume of the cannabinoid. In CBD oil tinctures specifically, potency is calculated by dividing the total CBD concentration by the volume of the cannabinoid. 

For instance, a 3000 mg in 60 ml bottle translates to a 50 mg/ml potency. The higher the concentration and the smaller the volume of your CBD oil tincture, the more potent CBD oils are. There are three types of CBD potencies for CBD oil tinctures; low-, medium-, and high-potency options, influencing your choice for CBD oil tinctures.

High-potency CBD oil tinctures refer to options with 50 mg/ml CBD or more. In fact, some brands have high-potency options with up to 200 mg/ml. 

High-potency CBD oil tinctures are great for saving on purchases. You only need a little of the CBD oil tinctures to feel the desired effects, hence why they are good for saving on a few bucks. Besides, high-potency CBD oil tinctures allow you to feel CBD effects fast. 

The cannabinoid reaches your system fast through the sublingual intake, and the volatile compounds allow the effects to come in no time. If you are a CBD veteran whose system can accommodate more CBD oil tinctures, high-potency options might be the best for your needs.

High-potency CBD oil tinctures are not all there are for these products. You can also go for the medium- or low-potency CBD oil tinctures. For instance, if you are a newcomer to the CBD regime, you need low-potency CBD oil tinctures until you are sure your system can accommodate more. Besides, if you take CBD oil tinctures for general well-being, you might be at home with the less potent options.


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  • Centers for Disease Control and Prevention. Sleep and Sleep Disorders. 
  • Forbes Health (2022). What to Know About Types of CBD. 
  • García-Gutiérrez, M. S., Navarrete, F., Gasparyan, A., Austrich-Olivares, A., Sala, F., & Manzanares, J. (2020). Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders. Biomolecules, 10(11), 1575. 
  • Massi, P., Vaccani, A., Bianchessi, S., Costa, B., Macchi, P., & Parolaro, D. (2006). The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. Cellular and Molecular Life Sciences CMLS, 63(17), 2057-2066. 
  • Mechoulam, R., & Parker, L. A. (2013). The endocannabinoid system and the brain. Annual review of psychology, 64, 21-47. 
  • Murillo-Rodríguez, E., Sarro-Ramírez, A., Sánchez, D., Mijangos-Moreno, S., Tejeda-Padrón, A., Poot-Aké, A., Guzmán, K., Pacheco-Pantoja, E., & Arias-Carrión, O. (2014). Potential effects of cannabidiol as a wake-promoting agent. Current neuropharmacology, 12(3), 269–272. 
  • Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente journal23, 18–041. 
  • Silote, G. P., Sartim, A., Sales, A., Eskelund, A., Guimarães, F. S., Wegener, G., & Joca, S. (2019). Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. Journal of chemical neuroanatomy, 98, 104-116. 
  • VanDolah, H. J., Bauer, B. A., & Mauck, K. F. (2019, September). Clinicians’ guide to cannabidiol and hemp oils. In Mayo Clinic Proceedings (Vol. 94, No. 9, pp. 1840-1851). Elsevier. 
  • Vučković, S., Srebro, D., Vujović, K. S., Vučetić, Č., & Prostran, M. (2018). Cannabinoids and pain: new insights from old molecules. Frontiers in pharmacology, 1259. 
  • Watt, G., & Karl, T. (2017). In vivo evidence for therapeutic properties of cannabidiol (CBD) for Alzheimer’s disease. Frontiers in pharmacology, 8, 20. 
  • Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International journal of molecular sciences19(3), 833. 

I am deeply convinced that each patient needs a unique, individual approach. Therefore, I use different psychotherapy methods in my work. During my studies, I discovered an in-depth interest in people as a whole and the belief in the inseparability of mind and body, and the importance of emotional health in physical health. In my spare time, I enjoy reading (a big fan of thrillers) and going on hikes.

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